Despite its benefits, Viagra is not suitable for everyone. Before starting treatment, it's essential for individuals to consult with a healthcare provider to ensure viagra commercial is a safe option based on their health status and sildenafil citrate price other medications they may be taking. It is contraindicated in individuals who take nitrates for heart disease, as mentioned, and those with certain health conditions such as severe liver impairment or can i buy doxycycline over the counter recent history of stroke or heart attack.
Moreover, ongoing research investigates the possible role of Viagra in treating conditions such as heart disease, stroke, and even premature ejaculation, indicating its versatile therapeutic potential beyond erectile dysfunction. It has shown potential in treating pulmonary arterial hypertension (PAH), a rare disease characterized by high blood pressure in the arteries of the lungs. Viagra, under the name Revatio, is prescribed to improve exercise ability and delay clinical worsening in PAH patients.
Besides treating ED, Viagra has also been explored for other medical conditions. It is advised to take the medication about one hour before sexual activity, and its effects can last up to four hours. Viagra is administered orally, typically in dosages ranging from 25 mg to 100 mg. However, it is important to note that Viagra does not increase sexual desire; it only helps to maintain an erection when sexual stimulation occurs.
Its introduction was a major breakthrough and it has since become a cultural phenomenon, often discussed openly in the media and in popular culture, which was unusual for any medication related to sexual health before its advent. Introduced to the market in 1998, Viagra was the first oral treatment approved by the FDA for erectile dysfunction. Viagra works by inhibiting an enzyme known as phosphodiesterase type 5 (PDE5), which is responsible for the breakdown of cGMP in the corpus cavernosum.
By blocking PDE5, Viagra enhances the effects of NO by prolonging the duration and effect of cGMP, thus improving the ability to achieve and maintain an erection in the presence of sexual stimulation. Normally, PDE5 breaks down a substance known as cyclic guanosine monophosphate (cGMP), which is crucial for the relaxation of smooth muscle tissue. By blocking PDE5, Viagra essentially increases the availability of cGMP, thereby enhancing the ability to achieve and maintain an erection.
The primary mechanism through which Viagra operates is by inhibiting an enzyme called phosphodiesterase-5 (PDE5). cGMP facilitates blood flow, and its increased levels result in better engorgement and function of the penis during sexual arousal. Erectile dysfunction is a condition where a man is unable to achieve or maintain an erection sufficient for satisfactory sexual performance. The introduction of Viagra has not only provided a reliable treatment option but has also helped diminish the stigma associated with ED, encouraging more men to seek help.
This condition affects millions of men worldwide and can have significant psychological and relationship impacts. It has helped break the stigma associated with erectile dysfunction, bringing more openness to discussions about sexual health among men. It has also spurred the development of other similar medications, such as tadalafil (Cialis) and vardenafil (Levitra), expanding the options available for erectile dysfunction treatment.
